stages of HIV infection
An untreated HIV infection takes place in several stages:
ACUTE HIV DISEASE
few days or weeks after the infection or infection occur flu-like symptoms (symptoms of AIDS), which in the rule undetected:
- persistent fever,
- head and body aches,
- muscle pain,
- nausea,
- continued massive diarrhea,
- prolonged night sweats,
- skin tumors or
- permanent swelling of the lymph nodes.
addition begins the explosive growth of the virus using the host cells, the CD4 cell surface proteins - the mainly found on T-lymphocytes (T-helper cells), to a lesser extent but also on monocytes, macrophages and B lymphocytes are - wear. This also leads to reduction of CD4-positive T-helper cells.
Note: This
temporary illness - acute HIV disease - is not with the disease AIDS - equivalent to - full screen.
LATENCY PHASE
This is a different length, usually multi-year phase of appearance of any physical discomfort, but the virus in the body increased. The immune system but, despite the proliferation of HIV and the destruction of T-helper cells still have the upper hand over the virus. This occurs because the damaged cells are replaced largely by the production of new cells.
AIDS-PHASE
The number of T-helper cells decreases and the viral concentration increases, so that without treatment in 9 to 10 years after initial infection to a severe immune defect occurs, ie the proportion of CD4-positive T-helper cells in the blood, which are important inter alia for the cellular immune system, decreases from usually 500 up to 1500 / mu.l to below 200/μl. This extreme immune deficiency that leads to AIDS disease takes so-called opportunistic infections and malignant complications - Kaposi's sarcoma, malignant lymphoma, HIV encephalopathy, wasting syndrome - being taken, which are usually the cause of death. Healthy but these pathogens are usually harmless.
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