A chip for cancer surveillance new method has cancer cells in blood of cancer patients after
A small microchip can cause cancer cells to fish out from a blood sample, the cells stick it to specially prepared micro-structures and can then be examined by doctors on. In lung cancer patients Shyamala Maheswaran, American researchers led by the cancer center at Massachusetts General Hospital in Charlestown now shown that this blood test to reliably similar follow-up a cancer therapy can be used as the usual, painful removal of tissue samples. From the genetic profile of the fished out tumor cells, the researchers want to determine which medication is best strike.
In microchip the blood sample flows through hair-thin channels and bathed in it about 78,000 micro-rods. On these rods are applied certain proteins that bind to the proteins of the tumor. In studies of 27 lung cancer patients, which was taken from ten milliliters of blood, the researchers found about a hundred tumor cells per milliliter of blood. A comparison with cell samples from biopsies showed that the researchers fished out the hope tumor cells with the tissue samples to 92 percent übereinstimmen.Die researchers to develop yet sophisticated laboratory technology to a simple blood test can continue. If that is the development of a lung disease and the course of therapy a blood sample instead of a tissue sample can be followed from inside the body. Tumor cells in the bloodstream means, according to the researchers do not necessarily mean that the cancer spreads it to other body regions. The amount of cancer cells in the blood can enter in some types of cancer information on how much the disease has progressed. By analyzing the genetic material of the tumor cell, researchers can also determine if the cancer by about mutations could develop a resistance to a drug. This would help in choosing the right therapy, say the researchers.
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